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San Francisco 49ers vs Arizona Cardinals Prediction & Result

Final Played · NFL

San Francisco 49ers36-30Arizona Cardinals

SprtGenie's AI pick for this american football game, published before kick-off and graded against the final score.

Our pick

AI pick
San Francisco 49ers
Moneyline: Home Win
Odds
-494
sportsbook price stored with the pick
Confidence
—
Risk: — · model probability 78%
Result
Won
graded against the final score

49ers’ 2-0 record, +42 point differential, and home advantage vs. Cardinals’ 1-1 mark and -12 differential.

Price and probabilities

SideMarket (no-vig)Fair priceOur model
San Francisco 49ers80%-38878%
Arizona Cardinals21%+38822%

Recent form

Last final scores before this game, from the results we grade our picks against.

San Francisco 49ers

Date (UTC)OpponentScoreResult
Sep 20, 2026vs Miami Dolphins35-13W
Sep 11, 2026@ Los Angeles Rams27-7W
Aug 28, 2026@ Las Vegas Raiders18-12W
Aug 21, 2026@ Los Angeles Chargers41-17W
Aug 14, 2026vs Tennessee Titans13-19L

Arizona Cardinals

Date (UTC)OpponentScoreResult
Sep 20, 2026vs Seattle Seahawks7-31L
Sep 13, 2026@ Los Angeles Chargers26-14W
Aug 29, 2026@ Green Bay Packers38-42L
Aug 23, 2026vs Dallas Cowboys13-34L
Aug 14, 2026@ Las Vegas Raiders27-14W

Every pick is graded in public

Wins, losses and pushes for every finished pick are on the SprtGenie track record, graded automatically against the official final score.

See the track record →More american football picks →

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Picks are AI-generated research, not betting advice, and past results do not guarantee future outcomes. SprtGenie is an informational research tool, not a sportsbook. 18+ only. If gambling is causing you problems, call the National Council on Problem Gambling at 1-800-522-4700.