Buffalo Bills vs Detroit Lions Prediction & Odds
Started . The final score and graded result appear here once the game is final.· NFL
SprtGenie's AI pick for this american football game, from analysis of live sportsbook odds, verified recent results and current news. After the game this page shows the final score and the graded result.
Our pick
- AI pick
- Buffalo Bills
- Moneyline: Home Win
- Odds
- -227
- sportsbook price stored with the pick
- Confidence
- —
- Risk: — · model probability 62%
- Result
- Pending
- graded automatically after the game
Bills’ superior Week 1 scoring margin and home-field edge in new stadium; Lions 1-0 but on short rest after OT win.
Price and probabilities
| Side | Market (no-vig) | Fair price | Our model |
|---|---|---|---|
| Buffalo Bills | 66% | -198 | 62% |
| Detroit Lions | 34% | +198 | 38% |
Recent form
Buffalo Bills
| Date (UTC) | Opponent | Score | Result |
|---|---|---|---|
| Sep 13, 2026 | @ Houston Texans | 36-31 | W |
| Aug 27, 2026 | vs Pittsburgh Steelers | 28-27 | W |
| Aug 22, 2026 | @ Cleveland Browns | 31-7 | W |
| Aug 15, 2026 | vs Carolina Panthers | 29-14 | W |
| Jan 17, 2026 | @ Denver Broncos | 30-33 | L |
Detroit Lions
| Date (UTC) | Opponent | Score | Result |
|---|---|---|---|
| Sep 13, 2026 | vs New Orleans Saints | 31-30 | W |
| Aug 29, 2026 | @ Indianapolis Colts | 25-16 | W |
| Aug 22, 2026 | vs Washington Commanders | 17-13 | W |
| Aug 13, 2026 | @ Cincinnati Bengals | 14-16 | L |
| Jan 4, 2026 | @ Chicago Bears | 19-16 | W |
Every pick is graded in public
Wins, losses and pushes for every finished pick are on the SprtGenie track record, graded automatically against the official final score.
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