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Arizona Cardinals vs Detroit Lions Prediction & Odds

Kick-off · NFL

SprtGenie's AI pick for this american football game, from analysis of live sportsbook odds, verified recent results and current news. After the game this page shows the final score and the graded result.

Our pick

AI pick
Detroit Lions
Moneyline: Away Win
Odds
-250
sportsbook price stored with the pick
Confidence
65%
Risk: Low · model probability 66%
Result
Pending
graded automatically after the game

Lions' 2-2 record, strong last-5 form, and superior scoring average increase win probability.

Price and probabilities

Best price for this pick
-250
at Bet365, the best of the sportsbooks we compared when the pick was published. Prices move; check the current price before acting.
SideMarket (no-vig)Fair priceOur model
Arizona Cardinals32%+21734%
Detroit Lions69%-21766%

Recent form

Last final scores before this game, from the results we grade our picks against.

Arizona Cardinals

Date (UTC)OpponentScoreResult
Oct 4, 2026@ New York Giants24-36L
Sep 27, 2026@ San Francisco 49ers30-36L
Sep 20, 2026vs Seattle Seahawks7-31L
Sep 13, 2026@ Los Angeles Chargers26-14W
Aug 29, 2026@ Green Bay Packers38-42L

Detroit Lions

Date (UTC)OpponentScoreResult
Oct 5, 2026@ Carolina Panthers26-32L
Sep 27, 2026vs New York Jets31-24W
Sep 13, 2026vs New Orleans Saints31-30W
Aug 29, 2026@ Indianapolis Colts25-16W
Aug 22, 2026vs Washington Commanders17-13W

Every pick is graded in public

Wins, losses and pushes for every finished pick are on the SprtGenie track record, graded automatically against the official final score.

See the track record →More american football picks →

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Picks are AI-generated research, not betting advice, and past results do not guarantee future outcomes. SprtGenie is an informational research tool, not a sportsbook. 18+ only. If gambling is causing you problems, call the National Council on Problem Gambling at 1-800-522-4700.